OSPA

投票結果

第211回（2014年2月14日）

*　発表者診断　　　　#　討論での主な対抗意見

1372 膀胱腫瘍 （物部泰昌先生）

Clear cell adenocarcinoma 6

　* of urinary bladder 2

　PAS:glycogen(++), 一部には粘液も。CK7(+)，CK20(-)，PSA(-)，CA19-9(++)
　MUC1(+)，MUC2一部(+)，MUC5AC(++)，MUC6(++)，PAX8(+)少数，HNF-1(+)少数
　　Hum Pathol 42: 1613-19, 2011
　　# 粘液細胞の混在をどの程度容認するか？

Adenocarcinoma 11

　　of urinary bladder 1

　　urachal 2

　　ductal, of prostate 2

　　prostatic 1

Urothelial carcinoma 9

　　with glandular differentiation 6

　　invasive, clear cell variant 1

　　papillary type 1

1373 右乳腺腫瘍 （黒田直人先生）

* Carcinoma with neuroendocrine features
　　with focal pleomorphic carcinoma 1

　一部にロゼット様構造あり　ER(++), PgR(+), HER2(-), Ki-67：80%, Synaptophysin(+)少数，CGA(-)，CD56(±)　　　Med Mol Morphol 42: 58-61, 2009
　　# 内分泌マーカーの陽性所見が弱いものをNET/NECの範疇に入れて良いのか？
Neuroendocrine (endocrine) carcinoma 3

　　solid 1

Carcinoma with neuroendocrine differentiation 1

Solid papillary carcinoma 6

　　invasive / with invasion 2

Medullary carcinoma 2

Invasive ductal carcinoma 6

　　neuroendocrine, with pleomorphic ca. Components 1

　　with medullary features 2

　　with pleomorphic features 1

Invasive carcinoma, no special type 4

　　with pleomorphic carcinoma component 2

　　Grade III and pleomorphic carcinoma 1

Metaplastic carcinoma 1

Squamous cell carcinoma 1

Myoepithelial carcinoma with focal squamous diff. 1

1374 子宮肉腫 （新宅雅幸先生）

Leiomyosarcoma 12

　* myxoid 2

　一部に benign lipoleimyoma 様の組織像あり　atypical lipocyte(-)　Ki-67(+++): myxoidな部でも高値

　AJSP 26: 142-149, 2002. Int J Gynecol Pathol 31: 358-363, 2012. Gynecol Oncol 39:381-383, 1990.

Lipoleiomyosarcoma 1

Liposarcoma 9

　　Pleomorphic 4

　　Dedifferentiated, from endometrial carcinosarcoma 1

Carcinosarcoma 1

Mesodermal mixed tumor 1

Malignant peripheral nerve cell tumor 1

Angiosarcoma 1

1375 馬尾腫瘍 （中山宏文先生）

Paraganglioma 9

　* spinal 1

　ト銀：Zellballen構造(+), chief cell・sustentacular cell・ganglion cellが混在，一部にganglioneuroma様の像も，Ki-67＜1％

　　of cauda equina / filum terminale 1

　　with ganglioneuromatous diff. 2

Gangliocytic paraganglioma 4

Ganglioneuromatous paraganglioma 1

Composite paraganglioma – ganglioneuroma 3

Ganglioneuroma 6

Ganglioneuromatous tumor 1

Ganglion cell tumor 1

Granular cell tumor 1

1376 皮膚腫瘍 （谷口恒平先生）

* Clear cell hidradenoma 12

　Am J Dermatopathol 31: 236-241, 2009. AJSP 36: 1835-1840, 2012.

Poroid hidradenoma 2

Eccrine hidradenoma, clear cell variant 1

Nodular hidradenoma 3

Hidradenoma 3

Sebaceoma 2

Mixed tumor 2

Eccrine hidrocystoma 1

1372	膀胱腫瘍	（物部泰昌先生）
	Clear cell adenocarcinoma			6
	* of urinary bladder		2
	PAS:glycogen(++), 一部には粘液も。CK7(+)，CK20(-)，PSA(-)，CA19-9(++) 　MUC1(+)，MUC2一部(+)，MUC5AC(++)，MUC6(++)，PAX8(+)少数，HNF-1(+)少数　　Hum Pathol 42: 1613-19, 2011 　　# 粘液細胞の混在をどの程度容認するか？
	Adenocarcinoma			11
	of urinary bladder		1
	urachal		2
	ductal, of prostate		2
	prostatic		1
	Urothelial carcinoma			9
	with glandular differentiation		6
	invasive, clear cell variant		1
	papillary type		1

1373	右乳腺腫瘍	（黒田直人先生）
*	Carcinoma with neuroendocrine features 　　with focal pleomorphic carcinoma			1
	一部にロゼット様構造あり　ER(++), PgR(+), HER2(-), Ki-67：80%, Synaptophysin(+)少数，CGA(-)，CD56(±)　　　Med Mol Morphol 42: 58-61, 2009 　　# 内分泌マーカーの陽性所見が弱いものをNET/NECの範疇に入れて良いのか？
	Neuroendocrine (endocrine) carcinoma			3
	solid		1
	Carcinoma with neuroendocrine differentiation			1
	Solid papillary carcinoma			6
	invasive / with invasion		2
	Medullary carcinoma			2
	Invasive ductal carcinoma			6
	neuroendocrine, with pleomorphic ca. Components		1
	with medullary features		2
	with pleomorphic features		1
	Invasive carcinoma, no special type			4
	with pleomorphic carcinoma component		2
	Grade III and pleomorphic carcinoma		1
	Metaplastic carcinoma			1
	Squamous cell carcinoma			1
	Myoepithelial carcinoma with focal squamous diff.			1

1374	子宮肉腫	（新宅雅幸先生）
	Leiomyosarcoma			12
	* myxoid		2
	一部に benign lipoleimyoma 様の組織像あり　atypical lipocyte(-)　Ki-67(+++): myxoidな部でも高値

	AJSP 26: 142-149, 2002. Int J Gynecol Pathol 31: 358-363, 2012. Gynecol Oncol 39:381-383, 1990.
	Lipoleiomyosarcoma			1
	Liposarcoma			9
	Pleomorphic		4
	Dedifferentiated, from endometrial carcinosarcoma		1
	Carcinosarcoma			1
	Mesodermal mixed tumor			1
	Malignant peripheral nerve cell tumor			1
	Angiosarcoma			1

1375	馬尾腫瘍	（中山宏文先生）
	Paraganglioma			9
	* spinal		1
	ト銀：Zellballen構造(+), chief cell・sustentacular cell・ganglion cellが混在，一部にganglioneuroma様の像も，Ki-67＜1％
	of cauda equina / filum terminale		1
	with ganglioneuromatous diff.		2
	Gangliocytic paraganglioma			4
	Ganglioneuromatous paraganglioma			1
	Composite paraganglioma – ganglioneuroma			3
	Ganglioneuroma			6
	Ganglioneuromatous tumor			1
	Ganglion cell tumor			1
	Granular cell tumor			1

1376	皮膚腫瘍	（谷口恒平先生）
*	Clear cell hidradenoma			12
	Am J Dermatopathol 31: 236-241, 2009. AJSP 36: 1835-1840, 2012.
	Poroid hidradenoma			2
	Eccrine hidradenoma, clear cell variant			1
	Nodular hidradenoma			3
	Hidradenoma			3
	Sebaceoma			2
	Mixed tumor			2
	Eccrine hidrocystoma			1